The DRD4 (Dopamine Receptor D4) Gene
This is a Neurodivergence blog post about the DRD4 (Dopamine Receptor D4) gene. Its position is Chromosome 11:637,269-640,706. I have been interested in this gene for almost two decades because of its connection to novelty seeking and Attention Deficit Hyperactivity Disorder (ADHD). Approximately 2.6% adults worldwide have persistent ADHD from childhood. Approximately 6.8% adults worldwide have symptomatic ADHD. Almost two decades ago, I got Thom Hartmann's book, The Edison Gene. It is based on the research studies of DRD4 7 Repeat allele which is present in 20% of the human population. DRD4 7R allele has high frequency in the Americas but low frequency in Asia. It has been strongly linked to both ADHD (Attention Deficit Hyperactivity Disorder) and a behavior trait called "novelty seeking" which often underlies addiction. Scientists suggest that DRD4 7R occurred recently in human evolution between 10,000 and 40,000 years ago which was the period that anthro...